The Marion Gluck Clinic

Hormone therapy and risk of cardiovascular outcomes and mortality in women treated with statins.

The aim of this study was to assess the effects of hormone replacement therapy on the risk of cardiovascular and all-cause mortality in women aged between 40 -74 who were receiving treatment with statins. A total of 40,958 statin users (2,862 hormone therapy users and 38,096 non-users) were followed for a mean of 4 years. Overall, the study found that among hormone therapy users, there were 5 cardiovascular deaths per 10,000 person-years; the corresponding rate for non-users was 18. The all-cause mortality rates were 33 (HT-users) and 87 (non-users). The authors concluded that hormone therapy is associated with a reduce risk of all-cause mortality in women who are receiving statins.

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