The Marion Gluck Clinic

Effect of dehydroepiandrosterone supplementation on bone mineral density, bone markers, and body composition in older adults. The Dawn Trial.

The aim of this randomised, placebo-controlled trail was to examine the effect of a daily dose of 50mg oral DHEA on the bone mineral density (BMD), bone metabolism and body composition in healthy adults aged between 55 and 85 years. The supplementation period lasted a year and they found that DHEA supplementation increased both serum DHEA and DHEA-sulphate levels to the concentrations measured in young adults 3 months into the study. Specifically, there was a positive effect of the supplementation on both lumbar spine BMD and C-terminal telopeptide (CTx) levels in the female group.

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